The oropharynx as a functional entity plays a fundamental role in feeding.Transitions from aquatic to terrestrial lifestyles in vertebrates demanded major changes of the oropharynx for the required adaptations to a different feeding environment.Extant turtles evolved terrestrial feeding modes in three families (testudinids, emydids, geoemydids)-ind
MYC up-regulation confers vulnerability to dual inhibition of CDK12 and CDK13 in high-risk Group 3 medulloblastoma
Abstract Background Medulloblastoma (MB) is the most common cerebellar malignancy during childhood.Among MB, MYC-amplified Group 3 tumors display the worst prognosis.MYC is an oncogenic transcription factor currently thought to be undruggable.Nevertheless, targeting MYC-dependent processes (i.e.transcription and RNA processing regulation) represent
Human Capital and Environmental Sustainability Nexus in Selected SADC Countries
This paper sought to examine the nexus between human capital and environmental sustainability in Southern African Development Community (SADC) countries.This contemporary topic has not received much attention in the region, Electric Knife hence the need to investigate the nexus between human capital and environmental sustainability.The paper used o
The Influence of Key Component Characteristic on the Resistance to Progressive Collapse of Composite Joint With the Concrete-Filled Steel Tubular Column and Steel Beam With Through Bolt-Extended Endplate
In this study, a finite element (FE) analysis of a composite joint with the concrete-filled steel tubular (CFST) column and steel beam, with a through bolt-extended endplate, was carried out in a progressive collapse.The reasonable constitutive model of a steel plate, through bolt and core concrete materials under a large deformation were selected,